Annular Epidermolytic Ichthyosis - Key Clinical Features

[1] Congential erythroderma

[2] Congenital blistering

[3] Superficial erosions in the neonatal period

[4] Subsequent hyperkeratosis (often linear, around flexures, sometimes predominates along the Blaschko lines)

[5] Palmoplantar hyperkeratosis

[6] Dramatic episodic flares of annular, polycyclic erythematous plaques with scale, which coalesce to involve most of the body surface and can persist for serveral weeks or even months