Epithelial Adhesion - Clinical Trials
Title: Self-Assembled Skin Substitute for the Treatment of Epidermolysis Bullosa
Recruitment: Active, not recruiting
Conditions: Epidermolysis Bullosa
Interventions: Biological: SASS
Title: Safety and Efficacy of Topical TolaSure Targeting Aggregated Mutant Keratin in Severe Epidermolysis Bullosa Simplex
Recruitment: Recruiting
Conditions: Epidermolysis Bullosa Simplex
Interventions: TolaSure Topical Gel versus Vehicle Topical Gel
Title: Injections of Botulinic Toxin in Plantar Lesions of Localized Epidermolysis Bullosa Simplex
Recruitment: Recruiting
Conditions: Epidermolysis Bullosa Simplex
Interventions: Botulinic toxin versus Placebo
Title: Gynecological Follow-up of Patients With Dystrophic Epidermolysis Bullosa (EBD)
Recruitment: Recruiting
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: Descriptive study of DEB
Title: A Neurokinin-1 Receptor Antagonist for the Treatment of Pruritus in Patients With Epidermolysis Bullosa
Recruitment: Active, not recruiting
Conditions: Epidermolysis Bullosa
Interventions: Serlopitant Tablet versus Placebo Oral Tablet
Title: Topical Beremagene Geperpavec (KB103) Gene Therapy to Restore Functional Collagen VII for the Treatment of Dystrophic Epidermolysis Bullosa
Recruitment: Active, not recruiting
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: Biological: topical beremagene geperpavec
Title: Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Recruitment: Active, not recruiting
Conditions: Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa
Interventions: Biological: EB-101
Title: A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa
Recruitment: Active, not recruiting
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: Biological: FCX-007 (dabocemagene autoficel)
Title: Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC
Recruitment: Recruiting
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: Rigosertib Sodium; Quality of Life Assessment
Title: Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa
Recruitment: Enrolling by invitation
Conditions: Junctional Epidermolysis Bullosa, Laryngo Onycho Cutaneous Syndrome
Interventions: no intervention
Title: Open-label, Pivotal Clinical Trial to Confirm Efficacy and Safety of Autologous Grafts Containing Stem Cells Genetically Modified for Epidermis Restoration in Patients With Junctional Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Junctional Epidermolysis Bullosa, Non-Herlitz Type
Interventions: Drug: Transplantation
Title: A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Recruitment: Active, not recruiting
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: Genetic: FCX-007
Title: Characteristics of Patients With Recessive Dystrophic Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: no intervention
Title: Gene Transfer for Recessive Dystrophic Epidermolysis Bullosa
Recruitment: Active, not recruiting
Conditions: Epidermolysis Bullosa Dystrophica/Epidermolysis Bullosa
Interventions: Biological: LZRSE-Col7A1 Engineered Autologous Epidermal Sheets
Title: Dose-ranging Study of Dentoxol® Mouthrinse for Managing Oral Symptoms in People With Epidermolysis Bullosa.
Recruitment: Enrolling by invitation
Conditions: Epidermolysis Bullosa
Interventions: Combination Product: Dentoxol mouthrinse dosages
Title: A Pilot Study to Explore the Role of Gut Flora in Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Epidermolysis Bullosa
Interventions: no intervention
Title: Extension Study to PTR-01-002
Recruitment: Enrolling by invitation
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: Drug: PTR-01
Title: Gentamicin for Junctional Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Junctional Epidermolysis Bullosa
Interventions: Drug: Gentamicin Sulfate
Title: Study of Cellutome System for Treatment of Individual Lesions in EB Pts
Recruitment: Active, not recruiting
Conditions: Epidermolysis Bullosa
Interventions: Device: Cellutome Epidermal Harvesting System
Title: MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs
Recruitment: Recruiting
Conditions: Epidermolysis Bullosa
Interventions: Thymoglobulin, Cyclophosphamide, Fludarabine, Total Body Irradiation, Bone marrow infusion, Tacrolimus, Mycophenolate Mofetil, Donor mesenchymal stem cell infusions, Busulfan
Title: Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: Drug: Gentamicin
Title: Biochemical Correction of Severe EB by Allo HSCT and "Off-the-shelf" MSCs
Recruitment: Active, not recruiting
Conditions: Epidermolysis Bullosa
Interventions: Cylophosphamide, Fludarabine, Anti-thymocyte globulin, Cyclosporin A, Mycophenolate mofetil, Mesenchymal stem cell transplantation, Total body irradiation, Bone marrow or umbilical cord blood stem cell transplantation
Title: INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Epidermolysis Bullosa Simplex, Junctional, Dystrophica, Kindler Syndrome
Interventions: INM-755 (cannabinol) cream versus Vehicle Cream
Title: Optimizing IV Gentamicin in JEB
Recruitment: Recruiting
Conditions: Junctional Epidermolysis Bullosa
Interventions: Drug: Gentamicin Sulfate, Injectable
Title: A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: Biological: Open Label Topical Beremagene Geperpavec (B-VEC)
Title: Ex Vivo Gene Therapy Clinical Trial for RDEB Using Genetically Corrected Autologous Skin Equivalent Grafts
Recruitment: Active, not recruiting
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: Biological: COL7A1-SIN retroviral vector engineered autologous tissue-engineered skin
Title: Rigosertib for RDEB-SCC
Recruitment: Recruiting
Conditions: Dystrophic Epidermolysis Bullosa, Squamous Cell Carcinoma
Interventions: Drug: Rigosertib oral capsules / Rigosertib intravenous
Title: The State of Sexual Development in Children With Inherited Epidermolysis Bullosa
Recruitment: Active, not recruiting
Conditions: Epidermolysis Bullosa
Interventions: Diagnostic Test: biochemical study of hormone levels, ultrasound examination, radiography of the hands, consultation of a medical psychologist
Title: Pregabalin Treatment for RDEB Pain and Itch
Recruitment: Active, not recruiting
Conditions: Epidermolysis bullosa
Interventions: Drug: Pregabalin
Title: Vitamin D Status and Bone Metabolism Status in Children With Congenital Epidermolysis Bullosa
Recruitment: Recruiting
Conditions: Epidermylosis Bullosa
Interventions: Drug: Vitamin D; oral nutritional supplement
Title: Long-Term Follow-up Protocol
Recruitment: Recruiting
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: no intervention; long-term safety of gene therapy products evaluated by Krystal Biotech, Inc., which have a shared backbone of HSV-1
Title: Computational Drug Repurposing for All EBS Cases
Recruitment: Recruiting
Conditions: Epidermolysis bullosa
Interventions: Experimental group
Title: Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
Recruitment: Recruiting
Conditions: Dystonin Related Epidermolysis Bullosa Simplex
Interventions: -