geneskin

Keratinization Disorders - Clinical Trials

Title: The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI Ichthyosis

Conditions: Ichthyosis
Interventions: TMB-001 versus Matching Vehicle
Recruitment: Recruiting

Title: An Open-Label and Long-Term Extension Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Patients With Ichthyoses

Conditions: Ichthyosis
Interventions: Ustekinumab
Recruitment: Recruiting

Title: Scientific Substantiation and Assessment of the Effectiveness of Pathogenetic Methods of Therapy for Congenital Ichthyosis in Children

Conditions: Congenital Ichthyosis
Interventions: Secukinumab Injection, Ustekinumab Injection, Dupilumab Injection, Symptomatic therapy
Recruitment: Recruiting

Title: Quality of Life in Middle-aged and Older Patients With Congenital Ichthyosis

Conditions: Congenital Ichthyosis
Interventions: Qualitative Interview
Recruitment: Recruiting

Title: Defining the Skin and Blood Biomarkers of Ichthyosis

Conditions: Ichthyosis, Netherton Syndrome
Interventions: -
Recruitment: Recruiting

Title: Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)

Conditions: TGM-1 Related Autosomal Recessive Congenital Ichthyosis
Interventions: Biological: KB105
Recruitment: Active, not recruiting

Title: Studies of Skin Microbes in Healthy People and in People With Skin Conditions

Conditions: Atopic Dermatitis, Eczema, Ichthyosis Vulgaris
Interventions: -
Recruitment: Recruiting

Title: The Role Of Neutrophil Proteases As Global Regulators Of Il-1 Family Cytokine Activity In Skin Disorders

Conditions: Psoriasis Vulgaris, Atopic Dermatitis, Ichthyosis Vulgaris
Interventions: -
Recruitment: Recruiting

Title: Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers

Conditions: Sjogren-Larsson-Syndrome (SLS)
Interventions: -
Recruitment: Active, not recruiting

Title: A Study to Assess the Safety and Pharmacokinetics of Single Ascending Subcutaneous and Intravenous Doses of DS-2325a in Healthy Subjects

Conditions: Netherton Syndrome
Interventions: Drug: DS-2325a versus Placebo
Recruitment: Recruiting

Title: Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome

Conditions: Netherton Syndrome
Interventions: QRX003-2% Lotion versus QRX003-4% Lotion versus Vehicle
Recruitment: Recruiting

Title: A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome

Conditions: Netherton Syndrome
Interventions: SXR1096 cream versus Placebo cream
Recruitment: Recruiting

Title: A Pilot Study of the Efficacy and Safety of Dupilumab Versus Placebo in Patients With Netherton Syndrome

Conditions: Netherton Syndrome
Interventions: Dupilumab Prefilled Syringe versus Placebo
Recruitment: Recruiting