Incontinentia Pigmenti - Key Clinical Features

(1) 4 stages of cutaneous eruption:

• vesiculo-bullous
• verrucous
• Swirling hyperpigmentation
• Atrophy/scarring

(2) Mild-moderate alopecia

(3) Coarse, wiry hair

(4) Nail dystrophy

(5) Hypodontia

(6) Peg-shaped teeth

(7) Retinal vascular abnormalities

(8) Microphthalmos

(9) Cataract

(10) Optic atrophy

(11) Mental retardation

(12) Seizures

(13) paralysis