CHILD Syndrome - Key Clinical Features

Skin abnormalities

  • congenital inflammatory skin lesions
  • unique lateralisation and strict midline demarcation
  • affinity to body folds (ptychotropism)
  • waxy yellowish scaling

Skeletal changes

  • minimal shortening of fingers or hypoplasia of one hand or foot
  • complete lack of bones and articular malposition
  • complete absence of extremities
  • stippled epyphyses


  • other organs such as the brain, heart, kidneys or eyes can be affected