Congenital Reticular Ichthyosiform Erythroderma - Key Clinical Features

(1) Ichthyosiform erythroderma at birth

(2) Ichthyotic patches in a reticulated pattern

(3) Palmoplantar keratoderma

(4) Appearance of white islands of healthy skin during childhood

(5) Healthy “confetti-skin” increases in size and number with age