X-Linked Recessive Ichthyosis - Key Clinical Features

Skin abnormalities

• polygonal dark scales (2/3 of the patients)
• light gray hyperkeratosis (1/3 of the patients)
• axillae and popliteal fossae may be involved
• lack of hyperlinear palms and soles

Others

• delayed cervical dilatation at birth
• testicular maldescent or cryptorchidism
• corneal opacities (normally not clinically relevant)